GENERAL CHARACTERISTICS OF GERD
Gastroesophageal reflux disease or GERD, is a very common disorder and occurs when stomach acid refluxes into the lower esophagus through the lower esophageal sphincter (LES). The LES is a band of muscles that act as a protective barrier against reflux material by contracting and relaxing. If this barrier is relaxed at inappropriate times or otherwise compromised, reflux occurs. Chronic or reoccurring reflux permits prolonged contact of stomach contents with the lower esophagus, leading to the symptoms of GERD. In general four underlying conditions are associated with GERD:

   1.

      Decreased lower esophageal sphincter pressure.
   2.

      Irritation of the lining of the esophagus by the stomach contents.
   3.

      Abnormal clearance of esophageal acid.
   4.

      Delayed stomach emptying. 

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A short video intro first, just in case you don't understand exactly what it is for - general description, side effects and warnings concerning nexium:

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A short video intro first, just in case you don't understand exactly what it is for - general description, side effects and warnings:

Nexium (Esomeprazole)

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